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Publications

CEND affiliates and fellows are research leaders - publishing new discoveries to accelerate progress against neglected and emerging diseases.

Publications

Structure–Activity Relationship Study of Antimalarial Asparagine-Derived Proteasome Inhibitors

Hao Zhang, Daqiang Li, Hao-Chi Hsu, Akshay Vishwanatha, Wenhu Zhan, Takafumi Yukawa, Joseph Visone, Toshihiro Imaeda, Rei Okamoto, Pavla Fajtova, Ryoma Hara, Masanori Kawasaki, Kenjiro Sato, Mayako Michino, Shreeya Garg, Oriana Kreutzfeld, Patrick K Tumwebaze, Stephen Orena, Martin Okitwi, Kazuyoshi Aso, Roland A Cooper, Philip J Rosenthal, Peter T Meinke, Michael Foley, Anthony J O’Donoghue, Huilin Li, Laura A Kirkman, Gang Lin

ORC binding to Heterochromatin Protein 1 through intrinsically disordered regions is required for heterochromatin structure and function

Yuchang Luo, Srivarsha Rajshekar, Harish Kumar, James M Berger, Gary H Karpen, Michael R Botchan

Structure and evolution-guided design of minimal RNA-guided nucleases

Petr Skopintsev, Isabel Esain-Garcia, Evan C DeTurk, Peter H Yoon, Zehan Zhou, Trevor Weiss, Maris Kamalu, Ajit Chamraj, Kenneth J Loi, Conner J Langeberg, Ron S Boger, Hunter Nisonoff, Hannah M Karp, Lin-Xing Chen, Honglue Shi, Kamakshi Vohra, Jillian F Banfield, Jamie HD Cate, Steven E Jacobsen, Jennifer A Doudna

A playbook for harmonization of standards for emergent viral pathogens

Sara Suliman, Sebastien Fuchs, David Catoe, Loren Hansen, Deepa Eveleigh, Michael A Crone, Paul S Freemont, Martin Kammel, Heinz Zeichhardt, Andrew T Anfora, Russell Garlick, Neil Almond, Mark Page, Brian Beck, Hui Wang, Karuna Sharma, Gary Pestano, Joannes Vancann, Jo Vandesompele, Adam S Corner, Jeffrey Albrecht, Deborah J Boles, Marcia Eisenberg, Ayla B Harris, Brian J Krueger, Amanda L Suchanek, Thomas J Urban, Jonathan D Williams, Patrick Chain, Alina Deshpande, Attelia Hollander, Sujata Chalise, David R Walt, Jeffrey Germer, Joseph D Yao, Bobbi S Pritt, Frederick S Nolte, Alexandra Bogožalec Košir, Mojca Milavec, Megan H Cleveland, Peter M Vallone, Eloise J Busby, Jim F Huggett, Denise M O’Sullivan, Elizabeth M Marlowe, Benjamin A Pinsky, Annaleise Kealiher, Jeantine E Lunshof, Christopher E Mason, John Sninsky, Cristina Tato, Timothy Mercer, Thomas J White, Marc Salit

Stochastic phylogenetic models of shape

Sofia Stroustrup, Morten Akhøj Pedersen, Frank van der Meulen, Stefan Sommer, Rasmus Nielsen

SSRI prescription during acute COVID-19 and risk of Long COVID symptoms and conditions among patients with depression

Zachary Butzin-Dozier, Yunwen Ji, Lin-Chiun Wang, Manav Kumar, A Jerrod Anzalone, Eric Hurwitz, Ariana Budhihartanto, Rena C Patel, Alan Hubbard, Jodi Halpern

Redox-activated cholesterol-dependent cytolysin enables cytosolic release of liposomal cargo

Seonhye Jang, Kundansingh Pardeshi, Suyeon Shin, ByeongJun Jeong, Sheng Zhao, Yalin Qi, Sung Tae Kim, Min Chul Park, Niren Murthy, Hansol Kim

How proteins fold

Carlos Bustamante, Christian M Kaiser, Erik Lindahl, Robert Sosa, Giovanni Volpe

Performance of an artificial intelligence model for evaluation of unnecessary central lines, Northern California 2025

Jenna M Wick, Apoorva Bhaskara, Wajeeha Tariq, Sean Lau, Mindy M Sampson, Jorge L Salinas

Design and characterization of 4D-710, an aerosolized gene therapy for cystic fibrosis lung disease

Melissa A Calton, Roxanne H Croze, Theodore H Sullivan, Sara A Collins, Sarah Tucker, Kevin J Whittlesey, Daniel H Kim, Julie A Nye, Ghezal Beliakoff, Melissa Quezada, Christian Burns, Chris Schmitt, Austin Klein, Vicky Jia, Laura Kovacs, Domokos Lauko, Kathryn Yoh, Kien Nguyen, Katherine Barglow, Johnny Gonzales, Devi Khoday, Thomas Mason, Kathy Delaria, Keenan Bashour, Melissa Kotterman, David Schaffer, An Song, Peter Francis, Jennifer L Taylor-Cousar, David Kirn

Evaluating the impact of antiviral post-exposure prophylaxis for health-care workers during ebolavirus outbreaks: a modelling study

Jacob N Stapley, Youngsuk Ko, Geetha Jeyapragasan, Elana MG Chan, Abel W Walekhwa, Cathal Mills, Christophe Fraser, Arthur L Reingold, Dav Ebengo, Christl A Donnelly, Placide K Mbala, Charles Whittaker

Black Patients Underdiagnosed With Long COVID In The US Compared With White Patients: Article examines Long COVID diagnosis for black patients and white patients

Zachary Butzin-Dozier, Yunwen Ji, Sarang Deshpande, A Jerrod Anzalone, Lin-Chiun Wang, Eric Hurwitz, Manav Kumar, Rena C Patel, Jing Sun, McKaylee Robertson, Andrew Mertens, Marlene Camacho-Rivera, John M Colford, Alan Hubbard, Charisse Madlock-Brown

Principal Components Analysis fails to recover phylogenetic structure in hominins

Levi Y Raskin, Maja Šešelj, Bárbara D Bitarello, Sofia Stroustrup, Jacky K Li, John Huelsenbeck

The Immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy

Cyrille L Delley, Sakshi Shah, Kevin M Joslin, Yujung P Park, Benjamin Demaree, Michael P Busch, Mars Stone, Steven G Deeks, Eli A Boritz, Adam R Abate, Iain C Clark

Harmonizing standards and resources for the medical genome

Euan A Ashley, Ash A Alizadeh, Hanae Armitage, Ami S Bhatt, Yair Blumenfeld, Andrew Carroll, R Martin Chavez, Petros Giannikopoulos, Megan E Grove, Meghan C Halley, Kiran Khush, Niall J Lennon, Samantha Maragh, Alexander Marson, Benedict Paten, Adam M Phillippy, Matthew H Porteus, Heidi L Rehm, Bradley R Ringeisen, Julia Salzman, Valerie A Schneider, Fritz J Sedlazeck, Lars M Steinmetz, Fyodor D Urnov, Stacia K Wyman, Justin M Zook, Lloyd B Minor, Jennifer A Doudna

Costs and impacts of vaccine preparedness investments for SARS-X pandemics

Patrick Doohan, Peter Windus, Andrew Torkelson, Damian Walker, Charles Whittaker, Gemma Nedjati-Gilani, Christian Morgenstern, Guillaume Morel, Marisa Miraldo, Giovanni Forchini, Fatima Docrat, Saul Walker, Dimitrios Gouglas, Alice Sabino, Katharina Hauck

Development and analytical validation of a fluorescent recombinase polymerase amplification-assay for real-time detection of Phyllosticta citricarpa, the causative agent of Citrus Black Spot

Federico La Spada, Rossana Parlascino, Mario Riolo, Sebastiano Conti Taguali, Antonella Pane, Matteo Garbelotto, Bryant Davenport, Marcos Amato, Santa Olga Cacciola