| Point of Contact | Lab/Research Group | Institution | Department | Current Activities | Available Facilities/Resources |
| Laurent Coscoy (lcoscoy@berkeley.edu) | Coscoy | UCB | MCB | Investigation the role of Covid E protein in activating a subset of T-cells with innate like properties | BSL3 lab; alveolar cell line |
| | CEND Drug Discovery Center / Cox | UCB | CEND | High-throughput screening to develop novel therapeutics | 130000 molecule HTS library; Sample mgt, state-of the art screening systems open to collaboration;
Screening lab BSL2+ |
| | Proteomics Lab/Kohlstaedt | UCB | QB3 | proteomics, inlcuding quant | |
| David AuCoin <daucoin@med.unr.edu> | Kozel/AuCoin Diagnostics Discovery Lab | UNR | Micro. & Immunology | mAb development, lateral flow immunoassay prototype development | Lateral flow immunoassay prototyping capabilities for the development of rapid diagnostics, hybridoma/mAb development, BSL-3 lab |
| Kate Pflughoeft <kpflughoeft@dxdiscovery.com> | DxDiscovery | DxDiscovery, Inc. (Reno, NV) | R&D | mAb development, lateral flow immunoassay prototype development | Lateral flow immunoassay prototyping capabilities for the development of rapid diagnostics, hybridoma/mAb development |
| Dave McIlwain <mcilwain@stanford.edu> | Garry Nolan Lab | Stanford | Micro. & immunology | Profiling host responses to infectious disease in humans and NHP models with single cell and tissue imaging techniques | Cytometry: CyTOF; High parameter tissue imaging: CODEX, MiBI |
| Chris Barker <cmbarker@ucdavis.edu> | Davis Arbovirus Research and Training (DART) Lab | UC Davis | Vet Med: Pathology, Microbiology, & Immunology | Arbovirus diagnostic testing (usually test mosquitoes and dead birds from across CA); not specifically interested in conducting research on COVID19 but could help if high-throughput testing capacity is needed. | RNA extraction, RT-qPCR; MagMax, QuantStudio 5 (2 each); BSL-2 & BSL-3 |
| Jimmie Ye(jimmie.ye@ucsf.edu) | Jimmie Ye lab/o | UCSF | DOM | single cell genetic and genomic studies to understand human immunity | single cell RNA-sequencing, surface marker and immune repertoire profiling, HPC compute environment |
| Matt Spitzer (matthew.spitzer@ucsf.edu) | Matt Spitzer lab | UCSF | Oto/M&I | systems immunology in cancer and infection, human and mouse | Immune profiling, CyTOF, data analysis/comp. bio |
| Bryan Greenhouse (bryan.greenhouse@ucsf.edu) | EPPIcenter research group / Greenhouse lab | UCSF | DOM | serosurveillance, ab kinetics in Bay Area and potentially Uganda | mathmatical modeling, Magpix, phage array, protein microarray, ELISA |
| Bin Yu (binyu@stat.berkeley.edu) | Yu Group | UCB | Statistics and EECS and CCB | data analysis (statistical and machine learning modeling) | statistical and machine learning mdoeling |
| Eluem.Blyden@avrilbiopharma.com | | Avril Biopharma | Protein Expression | Expression of Coronavirus proteins ( Spike, M) | BSL2 lab; Construct design and construction |
| Michal Tal (mtal@stanford.edu) | Weissman Lab/Tal Research Group | Stanford | ISCBRM | immune cell studies from human peripheral blood derived macrophages in response to pathogens (borrelia burgdorferi) as well as perturbing immune cells to enhance phagocytic capacity and clearance of tumor lines and bacteria | BSL2+ lab; a multitude of immunoassays; FACS expertise; isolation protocol for >95% pure and viable PBMC subsets from human blood; dedicated group for infectious disease research |
| Nicole Baumgarth (nbaumgarth@ucdavis.edu) | Baumgarth Lab | UC Davis | Vet Med: Pathology, Microbiology, & Immunology | Mouse modeling respiratory tract infections (influenza); serology, host response analysis | BLS2 and limited BSL-3 lab |
| Eluem.Blyden@avrilbiopharma.com | | Avril Biopharma | Computational Genomics | Structural Genetics analysis of public domain sequence data | Cloud computr platform; ML |
| Sarah McWirther smcwhirter@aduro.com | Aduro Biotech | Aduro Biotech | NA | | Aduro has a large amount of lab space available, willing to take in researchers/help in any capacity |
| Phil Berman (pwb@soe.ucsc.edu) | Berman HIV Vaccine Lab | UC Santa Cruz | Biomolecular Engineering | New technology for the rapid production of stable, high yielding CHO cell lines for the production of therapeutic monoclonal antibodies and glycan controlled vaccine immunogens for GMP production (>1 g/L in about 8weeks) | BSL2 + lab, Equipment for 3 L shakeflask cultures, engineered CHO cell lines to restrict glycosylation
engineered CHO cell lines to restrict glycosylation and proteolysis, AKTA purificatioon protein equipment
and proteolysis, AKTA protein purification protein equipment
Experience in writing CMC and Pre-clinical sections of INDs |
| Sarah McWirther smcwhirter@aduro.com | Aduro Biotech | Aduro Biotech | Chemistry/Regulatory/Clinical | | Chemistry expertise around Nucleotides as drugs; Library of Nucleotide-related molecules; clinical /regulatory/ manufacturing |
| Shirley Pan (shirley.pan@fibulas.com) | Fibulas | Citris Foundry | Skydeck | high fidelity sample preservation. We have medical grade technologies, products, lab and manufacturing facility which makes it possible for us to research and iterate efficiently. (We have products for swab samples, blood samples and other primary human cell/tissue samples) | 1) Sample collection preservation products, including: cryopreservation kits, sample swabs, viral preservation medium and containers, and other types of sample collection sets;
2) COVID-19 IgM Rapid Testing Kit (Chinese Official NMPA Approval)
3) COVID-19 Test PCR Reagent Kits (Chinese Official NMPA Approval)
4) SARS-COV-2 Artificial Viral Particle |
| Nevan Krogan; Kirsten Obernier (kirsten.obernier@ucsf.edu) | QBI Coronavirus Research Group (QCRG); about 25 labs at UCSF | UCSF | Quantitative Biosciences Institute (QBI) | QCRG, a newly formed research group at UCSF of over 25 laboratoris, is useing a combination of mass spectrometry, CRISPR-based genetics and structural analysis through Cryo-EM to understand how SARS-CoV-2 hijacks human cells for its own replication and to rapidly develop treatments - activities in brief: Protein-protein interaction maps of SARS-CoV-2 and human proteins for identification of host-dependency/restriction factors and novel drug targets - Affinity purification Mass Spec of all SARS-CoV-2 proteins and their host cell interactors; structural analysis (cryoEM, X-crystallography, XL-MS) of complexes, host factors, viral proteins; integrative modeling; docking studies; CRISPR-mediated functional genomics; drug screening | Mass Specs, CryoEM, constructs for each SARS-CoV-2 encoded protein, capabilities for large docking studies, etc |
| Parijat Bhatnagar (Parijat.Bhatnagar@sri.com) | Parijat Bhatnagar | SRI International | Biosciences | Engineering T cells for targeting viral diseases | T-cell engineering (e..g CAR T cells), in vitro BSL3 |
| Shirit Einav (seinav@stanford.edu) | Einav | Stanford | Medicine and Microbiology/Immunology | Screening for antivirals | Access to a BSL3 facility for in vitro and in vivo work via a collaborator at GMU |
| Anitha Jayaprakash | | Girihlet Inc | | TCR seqeuncing, alpha/beta, single cells, bulk. | can sequence covid samples free of cost, have a nextseq anyone wants to access is welcome. The Oakland Genomics Center has BSL2 facilty and work benches. |
| Michael Eckart (meckart@stanford.edu) | Shared Resource | Stanford | CMGM | Providing Genomic and protein analystical services | Oligo synthesis; Sanger DNA Sequencing/Fragment Analysis; qPCR; Peptide synthesis; SPR (Biacore) |
| Naresh Sunkara (naresh@berkeley.edu) | | UC Berkeley | | At UC Berkeley, we are about to launch a major effort to establish a make-shift CLIA grade testing center. Volunteers will be trained under CLS standards with appropriate safety measures., we are trying to see the interest levels of grad students and postdocs in helping expand the testing capabilities around the country. Procedures like rRT-PCR and working in BSL-2/3 labs is a routine in university and national labs. We believe that if we can have trained volunteers to assist carry out assays, we can expand our testing capabilities exponentially. Please signup if you think you would be able to help out. Sign Up Here | |
| Diego Rey (diego@rey.bio) | NA | Roche | Diagnostics | Lab space may be available for use (e.g. testing, kitting) | 10,000+ sqft BSL2 lab |
| Melanie Ott (melanie.ott@gladstone.ucsf.edu) | Ott Lab | UCSF | Virology & Immunology | Developing rapid, POC diagnostics; infection of primary lung organoids for scRNA-seq/compound screening/CRISPR screening; expression constructs of SARS-CoV-2 proteins for functional screens | BSL3; viral protein library |
| Lark Coffey (lcoffey@ucdavis.edu) | Davis Arbovirus Research and Training | UC Davis | Pathology, Microbiology and Immunology | Interested in sequencing and potentially infectious virus work in cells and or small animal models | BSL-2 space, 2 BSL-3 facilities including ABSL-3, RT-qPCR, deep sequencing |
| Lisa Diamond (lisa.diamond@pinpointscience.com) | Bay Genomics lab | Pinpoint Science Inc. | Diagnostics | Prototyping and validating 30-second handheld Covid-19 test based on novel nanosensor technology derived from Pourmand lab work at UC Santa Cruz. | BSL2 lab |
| Rebecca DuBois (rmdubois@ucsc.edu) | Protein Engineering | UC Santa Cruz | Biomolecular engineering | Subunit vaccines, virus antigen-antibody structures | Recombinant protein production, BSL-2 |
| Reza Abbasi-Asl (Reza.AbbasiAsl@ucsf.edu) | Abbasi Lab | UCSF | Neurology | Computational modeling and machine learning | Computational support and modleing based on machine learning principles |
| Lyndsay Murrow | Gartner Lab | UCSF | Pharmaceutical Chemistry | single cell studies to understand cell communities and tissues | MULTI-Seq reagents for sample multiplexing of scRNAseq experiments |
| Bonnie Kim (bonnie@codexdna.com) | CODEX-DNA (formerly known as SGI-DNA) | | | COVID research resources - available at https://codexdna.com/pages/sars-cov-2-tools | 1. SARS-CoV-2 diagnostic RNA controls
2. SARS-CoV-2 antigen panels
3. SARS-CoV-2 antibody libraries
4. SARS-CoV-2 spike protein DNA vaccine construct
5. SARS-CoV-2 mRNA vaccine scaffold
6. SARS-CoV-2 live attenuated vaccine scaffold
7. SARS-CoV-2 synthetic DNA parts
8. SARS-CoV-2 full length, synthetic genome
9. BioXp 3200 |
