Hengyuan Shen, Zhenling Wang, Kevin Ikeda, Dong Jun Shin, Matthias Loipersberger, Alexander Zech, Stefan Huber, Teresa Head-Gordon, Martin Head-Gordon
Publications
CEND affiliates and fellows are research leaders - publishing new discoveries to accelerate progress against neglected and emerging diseases.
The Impact of Respiratory Syncytial Virus Undertesting on Estimates of Disease Burden and Vaccine Effectiveness in a Large Integrated Healthcare System
Bradley K Ackerson, Brandon Chia, Negar Aliabadi, Gabriella Goodwin, Jeff Slezak, Vennis Hong, Qing Liu, Sally Shaw, Sabrina Welsh, Julie A Stern, Banshri Kapadia, Brigitte C Spence, Joseph A Lewnard, Gregg Davis, Evan J Zasowski, Michael Aragones, Ashley Miller, Michael Dutro, Erica Chilson, Elisa Gonzalez, Robin Hubler, Luis Jodar, Bradford D Gessner, Elizabeth Begier, Sara Y Tartof
A curated benchmark for cofolding models on kinase conformational states
Kunyang Sun, Teresa Head-Gordon
High rates of congenital CMV infection in a highly CMV-endemic Ugandan population
Amy KF Davis, Mary Prahl, Mikias Ilala, Justine Levan, Pam M Odorizzi, Mary K Muhindo, Abel Kakuru, Moses R Kamya, Grant Dorsey, Margaret E Feeney
Oil and gas well development and coccidioidomycosis risk in Kern County, CA, USA: a case-crossover study
Lisa I Couper, David JX González, Simon K Camponuri, Amanda K Weaver, Gail L Sondermeyer Cooksey, Duc Vugia, Seema Jain, John Taylor, John Balmes, Ellen A Eisen, Justin V Remais, Jennifer R Head
Therapeutic blockade of IL-1β in PWH reduced the HIV reservoir via mechanisms of enhanced CD8 and CD4 effector function and reversal of monocyte dysfunction
Ashish Arunkumar Sharma, Meghana Dropathi, Naseem Sadek, Danny Li, Ashok K. Dwivedi, David Siegel, Rachel Rutishauser, Steven Deeks, Priscilla Hsue, Sulggi Lee, Rafick-Pierre Sekaly and Jeffrey Alan Tomalka
Gravidity-dependent protection against placental malaria is associated with enhanced natural killer cell-mediated antibody-dependent cellular activation: a nested cohort study
Savannah N Lewis, Alea Delmastro, Mary Lopez-Perez, Sonia Presti, Adam S Kirosingh, Felistas Nankya, Kenneth Musinguzi, Jimmy Kizza, Abel Kakuru, Michael Ofori, James Dressman, Sean C Bendall, Grant Dorsey, Philip J Rosenthal, Moses R Kamya, Kattria van der Ploeg, Lars Hviid, Prasanna Jagannathan
Barcoded mutant library enables high-throughput functional genomics in a filamentous fungus
Lori B Huberman, José M Villalobos-Escobedo, Jeffrey M Skerker, Ran Shi, Adriana M Rico-Ramírez, Catharine A Adams, Adam P Arkin, Adam M Deutschbauer, N Louise Glass
Improving RNA secondary structure prediction through expanded training data
Conner J Langeberg, Taehan Kim, Roma Nagle, Agni Rajinikanth, Charlotte Meredith, Dimple A Garuadapuri, Jennifer Doudna, Jamie Cate
Singlet Photoredox Catalysis via Supramolecular Host–Guest Interactions
Sean M. Treacy, Aila V. Rothweiler, Cody Son Tran, Ainsley M. Clark, Daniel Deng, Nabil Mouhajir, Martin Head-Gordon, Kenneth N. Raymond, Robert G. Bergman, F. Dean Toste
How Should We Treat Severe Malaria in the Setting of Artemisinin Partial Resistance?
Philip J Rosenthal, Moses R Kamya, Ruth Namazzi, Chandy C John
Bradykinin contributes to vasogenic edema in murine experimental cerebral malaria
Alessandro de Sa Pinheiro, Douglas E Teixeira, Rodrigo P Silva-Aguiar, Young Jun Shim, Alona A Merkulova, Sadiq Silbak, Yelenna Skomorovska-Prokvolit, David Midem, Sidney Ogolla, Bjoern B Burckhardt, Tanja Gangnus, Julio Scharfstein, Celso Caruso-Neves, Owen JT McCarty, David Gailani, Michael Bader, Philip J Rosenthal, Arlene E Dent, Chris J Janse, Keith R McCrae, Ana Acacia de Sa Pinheiro, James W Kazura, Alvin H Schmaier
Targeted Knockout of CYP79A1 Reduces Cyanogenic Potential in Grain Sorghum
Evan D Groover, Jianqiang Shen, Kiflom Aregawi, Sophie Li, Shahar Schwartz, Brian J Staskawicz, Peggy G Lemaux, David F Savage
Semi-supervised retrieval of functional residues through the integration of protein language models and gene ontology data
Andrew Dickson, Safaa Mouline, Ali Tamadon, Mohammad RK Mofrad
Turning a biochemical GatCAB inhibitor into a live-cell active antibacterial probe through lipid and trehalose conjugation
Chawarat Isarangkool Na Ayutthaya, Anon Boonkerd, Wanchat Sirisarn, Nattanan Panjaworayan T-Thienprasert, Borvornwat Toviwek, Prapasiri Pongprayoon, Hemant Joshi, Babak Javid, Pitak Chuawong
The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology
Eliane Hadas Yardeni, Dóra Judit Kiss, Julie Sanchez, Keshet Shavit, Dénes Szepesi Kovács, Attila Egyed, Caleb D Vogt, Supriya A Gaitonde, Jacqueline Glenn, Meritxell Canals, Michel Bouvier, Amy Hauck Newman, J Robert Lane, György M Keserű, Moran Shalev-Benami
Aiptasia larvae are phenotypically validated as a model of coral bleaching using high-throughput machine-learning image analysis
Iyla Rossi, Emily K Meier, Dania Nanes Sarfati, Francisco Guadalupe Zamora, Samantha Fung, Phillip A Cleves, Amy Herr
LNP-mediated BCL11A Editing Corrects Sickling Phenotypes and Preserves HSPC Fitness Compared to Electroporation
Yaw Ansong-Ansongton, Corynne SA Adanho, Utku Goreke, Atip Lawanprasert, Mikhail Vysotskiy, York Tang, Alissa LW Kleinhez, Ross Wilson, Angela Rivers, Niren Murthy, David N Nguyen
Lipid Nanoparticle Protein Coronas Arise through Lipoprotein Fusion Rather Than Shell-like Adsorption
Shaun Grumelot, Naseeha Mohammed, Ghafar Yerima, Jorge Colonrosado, Seyed Amirhossein Sadeghi, Fei Fang, Kylie Hilsen, Brooke Shango, Amir Ata Saei, Amanda M Murray, Michael J Mitchell, Babak Borhan, Liangliang Sun, Hojatollah Vali, Mohammad RK Mofrad, Kathryn A Whitehead, Morteza Mahmoudi
Emerging Patterns of Heat and Wildfire Smoke at California Correctional Facilities
Rachel Sklar, Samantha Kramer, Marissa Childs, Cecilia Martindale, Frederick Lurmann, Beck Kiely, Xinyang Li, Stefano Bertozzi, Elizabeth Noth